In the program COGNITOR each protein in the proteome is used as a query of a database of protein clusters.
a) True
b) False
Q.2.
WU-BLAST produces P scores and BLAST (NCBI) produces E scores where _________
a) E = ln (1 + P2)
b) E = ln (1 – P2)
c) E = ln (1 + P)
d) E = ln (1 – P)
Q.3.
In Proteolysis and fragment sequencing, Protein spots may be excised from a two-dimensional protein gel and subjected to a combination of amino acid sequencing and cleavage analyses using the techniques of mass spectrometry and high-pressure liquid chromatography.
a) True
b) False
Q.4.
In Proteingel Electrophoresis, Individual proteins produced by the genome can be separated to _____ by this method and specific ones identified by various _______
a) smaller extent, biochemical and immunological tests
b) a large extent, biochemical and immunological tests
c) a large extent, biochemical tests only
d) smaller extent, purely mechanical tests
Q.5.
In Metabolic pathways and regulation, as genes are identified in a new genome sequence, some will be found that are known to act sequentially in a metabolic pathway or to have a known role in gene regulation in other organisms.
a) True
b) False
Q.6.
_______ of the Drosophila sequence is composed of TEs and _____ is heterochromatic regions that do not include genes.
a) one-fourth, one-third
b) one-fifth, one-fourth
c) one-sixth, one-eighth
d) one-sixth, one-third
Q.7.
Yeast is about ______ compact than E. coli.
a) fivefold, less
b) threefold, more
c) twofold, less
d) twofold, more
Q.8.
The ________ are _______ by genetic structure to retroviruses.
a) STR retrotransposons, related
b) LTR retrotransposons, related
c) STR transposons, related
d) LTR retrotransposons, not related
Q.9.
Which of the given statement is incorrect?
a) As in an all-by-all protein comparison within a proteome, a matrix of alignment scores with E values is made, and the most closely related sequences in the two organisms are identified
b) To perform a between-proteome analysis, proteome databases are made for the known and predicted genes of two or more genomes
c) Each protein of one proteome is selected in turn as a query of the proteome of another organism or the combined proteome of a group of organisms
d) Each protein of one proteome is selected in turn as a query of the proteome of another single organism only
Q.10.
The higher the E value, the more significant the alignment between a pair of matching sequences.
a) True
b) False
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