Cyclin-CDK complex (here considering S cyclin) when active is responsible for phosphorylating several proteins and this often marks then for destruction by ubiquitination. What would be its effect on Cdt activity?
a) Activation
b) Inactivation
c) Destruction
d) Increased synthesis
Q.2.
Which of these would you use as a competitive inhibitor for Cdt?
a) MCM 1
b) MCM 2
c) MCM 7
d) MCM 10
Q.3.
What is the fate of phosphorylated Cdc 6?
a) It is transported outside nucleus
b) It is ubiquitinylated
c) It gets activated
d) It forms a complex with Cdt
Q.4.
Pre-replication complex is necessary to initiate replication. It assembles in______________
a) Late Anaphase
b) G1 phase
c) S phase
d) Early Anaphase
Q.5.
Which Cyclin-CDK complex will you find most active in M phase?
a) Cyclin A- CDK 2
b) Cyclin B- CDK 1
c) Cyclin D- CDK 2
d) Cyclin E- CDK 1
Q.6.
What is the DNA composition of ARS?
a) A-T rich
b) G-C rich
c) Repeating A-T, G-C sequence
d) No specific sequence speciality
Q.7.
In an experiment, you are working on mitochondrial chromosomes. Which polymerase will ensure accurate replication?
a) pol beta
b) pol delta
c) pol iota
d) pol gamma
Q.8.
To your cultured cell lines, you add growth factors like cytokines which act through MAPK cascade pathway. Which transition will it trigger?
a) S->G2
b) M->Anaphase
c) G1->S
d) G2->M
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