Do not allow riders to leave carry-on baggage in any doorway or aisle. There should be nothing in the aisle that might trip other riders. Secure baggage in a way that prevents damage.

Tank vehicles have high centers of gravity, which makes them vulnerable to rollover.

Before loading or unloading a tank with flammable liquids, you should turn off the engine, unless running the engine is necessary to operate a pump. Ground the tank before opening the filling hole and maintain the ground until after closing the filling hole.

The United States Department of Transportation (DOT)’s Emergency Response Guidebook (ERG) lists all hazardous chemicals and their assigned identification numbers.

An operator should drive with care when transporting a cargo of hanging meat. Such a load is unstable, both because it has a high center of gravity and because the swinging of the meat can affect the driver's handling of the vehicle.

Some tanks are divided into multiple smaller tanks by bulkheads. When loading or unloading such tanks, pay attention to weight distribution. Be careful not to place too much weight on a single end of the tank.

Be sure to inspect your vehicle before driving. Never drive a tank vehicle with open valves or manhole covers.

Keep liquid discharge valves on a compressed gas tank closed, except when loading and unloading.

A bus should not be refueled while passengers are on board, unless it is absolutely unavoidable. A bus with passengers on board should never be refueled inside an enclosed building.

Underloading a front axle may make it impossible to safely steer your vehicle. Keep weight distribution in mind when loading cargo.

If you are experiencing a truck fire, you should not attempt to open trailer doors without first feeling the doors to see if they are hot. If the doors are hot, there may be a cargo fire. Leave the doors closed if there is a cargo fire.

When carrying Division 1.1, 1.2, or 1.3 explosives, do not park within 300 feet of a bridge, tunnel, or building; a place where people gather; or an open fire.

Because liquids expand when their temperatures increase, some space must be left in a tank to accommodate the expansion. This space is referred to as "outage." The amount of required outage is different for different liquids.

When inspecting any style of tank, the most important thing for a driver to check for is leaks. Transporting any type of gas or liquid in a leaking tank is illegal.

Containerized loads are generally used when freight is carried partway by rail or ship. Sealed materials cannot be inspected, but a driver should ensure that the containers do not exceed safe and legal weight limits.

It is the driver's responsibility to inspect their cargo; recognize overloading or poorly balanced weight; know that the cargo is properly secured and does not obscure the driver's view; and know that the cargo does not restrict access to emergency equipment. The driver is responsible for their cargo even if they were not the one who initially loaded and secured the cargo.

A "G" in Column 1 of a hazardous materials shipping paper indicates that the description in Column 2 is the generic name for a material. A generic shipping name must be accompanied by a technical name.

Baffled and unbaffled bulkheads in tanks serve to inhibit the forward and backward surge of liquid cargo.

Particularly on curves, the maximum posted speed limit may be safe to be driven in a car but too fast to be driven in a bus. Be especially careful when the road has been made slippery by rain or snow.

On flatbed trailers and trailers without sides, cargo must be tied down. There should be at least one tie-down for every 10 feet of cargo. Regardless of the size of the cargo, at least two tie-downs must be used.