Driving a combination vehicle usually requires more skill than driving a single vehicle. Combination vehicles are generally longer and heavier than single commercial vehicles.

The easiest way to spot a trailer skid is to use your mirrors. Any time you brake hard, check your mirrors to ensure that your trailer is still in its proper position.

When coupling, make sure you couple matching glad hands. They are often color-coded to help drivers avoid mistakes. Typically, blue is used for service lines and red is used for emergency lines.

The trailer hand valve should not be used for parking. This could cause all of the air to leak out of the braking system, resulting in the brakes releasing. Instead, use the parking brake.

Never use the trailer hand valve while operating your vehicle. Using the trailer hand valve while driving can cause your trailer to skid.

Tractor protection controls in older vehicles may be operated by levers instead of knobs. If an air supply control is set in its "emergency" position, the air supply will be stopped and the trailer emergency brakes will be applied.

Triple combination trailers are most vulnerable to the "crack-the-whip" effect.

Before a trip, ensure that air in the air brake system reaches all trailers. Do this by waiting for air pressure to build, then sending air to both the emergency and service lines and opening the shut-off valves on the rear of the last trailer. If air escapes from the shut-off valves in the rear of the combination, the air is being supplied to the entire vehicle.

The service air line carries air and is controlled by either the foot brake or trailer hand brake. The service air line is attached to relay valves, which allow the trailer brakes to be applied quickly.

Railroad-highway crossings may be difficult to cross when pulling a trailer with a low underneath clearance. In particular, both low-slung units and single-axle tractors pulling long trailers are especially challenging to drive over raised crossings.

Combination vehicles require more space on the road than other vehicles. When entering or crossing traffic while driving a combination vehicle, it is especially important that there is a large enough gap in traffic for you to safely do so.

Large combination vehicles take longer to stop when they are empty than when they are loaded. The decreased weight causes a vehicle's wheels to have decreased traction on the surface of the road.

An empty combination vehicle will come to a complete stop more slowly than a fully-loaded vehicle. The stiff suspension springs and strong brakes will have lower traction on a light trailer than they would if the vehicle carried more weight.

Because the weight of cargo gives them a higher center of gravity, fully-loaded rigs are 10 times more likely to roll over in a crash than empty rigs.

A rollover is more likely if cargo is unevenly loaded in a rig. To help prevent a dangerous rollover, it is important to keep a load as centered on the rig as possible.

The trailer hand valve, also called the trolley valve or Johnson bar, is used to work the trailer brakes. It should be used only to test the brakes.

Shut-off valves are used in air supply lines to control the passage of air from one trailer to another. The rear shut-off valve should always be closed to prevent air from leaving the braking system.

Failure to keep the fifth wheel plate properly lubricated can create friction between the tractor and trailer, causing steering problems.

On combination vehicles with air brakes, the tractor protection valve keeps air in the tractor or truck brake system, should the trailer develop a bad leak or break away from the tractor.

An empty trailer will require a longer stopping distance than a loaded trailer. Additionally, a trailer is most likely to swing out and strike other vehicles when it is lightly loaded or empty.