Q.1.
Chromosomal condition of Down's syndrome is .... ...
-
18%
a) Allosomal hypoaneuploidy
-
64%
b) Autosomal aneuploidy
-
9%
c) Allosomal hyper-aneuploidy
-
9%
d) Partial autosomal deletion
Q.2.
Tay Sachs disease is due to ... .. [ AMU 2003 ]
-
44%
a) Sex-linked recessive gene
-
44%
b) Sex-linked dominant gene
-
11%
c) Autosomal dominant gene
-
0%
d) Autosomal recessive gene
Q.3.
Cri-du-char syndrome is due to chromosomal change involving ... ...[ AFMC 2008]
-
14%
a) Duplication
-
14%
b) inversion
-
43%
c) Deletion
-
29%
d) Translocation
Q.4.
Scientist who was awarded Nobel prize for finding genes to be linearly arranged on chromosomes was ... ... [ Kerala 2001 ]
-
12%
a) Wolf
-
50%
b) Punnet
-
38%
c) Morgan
-
0%
d) Knight
Q.5.
Which one is correctly matched? ... .. [ WB 2009 ]
-
38%
a) Sickle cell anaemia --- X-chromosome
-
0%
b) Haemophilia --- Y-chromosome
-
50%
c) Down's syndrome --- 21st chromosome
-
12%
d) Parkinson's disease --- XY chromosome
Q.6.
Mutation refers to sudden change in ... ... [ Pb PMT 1998 ]
-
29%
a) Phenotype
-
0%
b) Maturation time
-
43%
c) Metabolic rate
-
29%
d) Genetic make up
Q.7.
Haemophilic man marries a carrier woman. percentage of daughters becoming haemophilic shall be .... .. [ BHU 1990]
-
25%
a) 0%
-
25%
b) 50%
-
25%
c) 75%
-
25%
d) 100%
Q.8.
gene for diabetes mellitus is ... ... [ BHU 2012 ]
-
14%
a) Autosomal dominant
-
14%
b) Autosomal recessive
-
57%
c) Sex-linked dominant
-
14%
d) Sex-linked recessive
Q.9.
Colchicine interferes with ... ... [kerala 2000]
-
50%
a) Chromosome replication
-
33%
b) Organization of spindle
-
0%
c) Chromosome condensation
-
17%
d) Incorporation of nitrogen bases
Q.10.
Human genome project was started in .... ....
-
25%
a) 1989
-
25%
b) 1990
-
50%
c) 1992
-
0%
d) 1995
Q.11.
out of A-T, G-C pairing bases of DNA may exists in alternate valency state called... .. [ WB2009]
-
57%
a) Tautomerisational mutation
-
14%
b) Analogue substitution
-
0%
c) point mutation
-
29%
d) Frame shift mutation
Q.12.
A mutation in DNA molecule involving replacement of one nucleotide base pair with another is .... ... [ MPPMT 2010]
-
38%
a) Point mutation
-
62%
b) Frame-shift mutation
-
0%
c) Deletion mutation
-
0%
d) A transposon
Q.13.
Cis-trans expression of gene is an example of .... [ DPMT 1996]
-
75%
a) Mutation
-
0%
b) Intragenic crossing over
-
25%
c) Intergenic crossing over
-
0%
d) Cytoplasmic inheritance
Q.14.
Heterochromatic region is .... .. [ Manipal 2004 ]
-
0%
a) Genetically more active
-
86%
b) Genetically less active
-
14%
c) loosely coiled region
-
0%
d) Lightly coloured region
Q.15.
Genes for colour blindness/sex linked traits are located on .. ... [ DPMT 2002 ]
-
33%
a) X-chromosome
-
50%
b) Y-chromosome
-
17%
c) X or Y-chromosome
-
0%
d) Both X and Y chromosomes
Q.16.
Depending upon distance between two genes, cross-over will vary from... ... [ AMU 2012 ]
-
17%
a) 50 -100%
-
50%
b) 75 -100%
-
17%
c) 10 ∼ 50%
-
17%
d) 0 - 50%
Q.17.
Select the correct bases of DNA, RNA and amino acid of beta chain causing sickle cell anaemia ... ... [ kerala 2009 ]
-
20%
a) DNA: CAC-GUG ; RNA: GAG ; Amino acid: Glutamic acid
-
0%
b) DNA: CAC-GTG ; RNA: GUG ; Amino acid: Valine
-
40%
c) DNA: CTC-GAG ; RNA: GUG ; Amino acid: Valine
-
40%
d) DNA: CAC-GTG ; RNA: GAG ; Amino acid: Glutamic acid
Q.18.
The symbol of empty circles used in pedigree analysis represnts ... .. [ manipal 2000]
-
75%
a) Normal females
-
25%
b) Normal males
-
0%
c) Affected females
-
0%
d) Affected males
Q.19.
Eukaryotic chromosome is made of ... .. [ RPMT 2006 ]
-
0%
a) DNA
-
80%
b) DNA + protein
-
20%
c) DNA + lipids
-
0%
d) RNA
Q.20.
phenotypically females having rudimentary ovaries, underdeveloped breasts, short stature, webbing neck, often subnormal intelligence suggests ... [ CET Chd. 2010]
-
25%
a) Down's syndrome
-
50%
b) Klinefelter's syndrome
-
25%
c) Turner's syndrome
-
0%
d) Haemophilic syndrome
Q.21.
Epicanthus is symptom of ... ... [ KCET 2001 ]
-
20%
a) Haploidy
-
20%
b) Turner's syndrome
-
60%
c) Down's syndrome
-
0%
d) Heteroploidy
Q.22.
Type of chromosomal aberration in diagram shows .... ..[ kerala 2005 ]
-
25%
a) Interstitial translocation
-
25%
b) Reciprocal translocation
-
50%
c) Paricentric translocation
-
0%
d) Interstitial translocation
Q.23.
Mental retardation in man associated with sex chromosomal abnormality is due to .... ... [ CBSE 1998 ]
-
20%
a) increase in X-complement
-
20%
b) decrease in X-complement
-
60%
c) large increase in Y-complement
-
0%
d) moderate increase in Y-complement
Q.24.
Patterns baldness, moustaches and beard in human males are examples of ... .. [ CBSE 2003 ]
-
33%
a) Sex-linked traits
-
17%
b) Sex differentiating traits
-
33%
c) Sex limited traits
-
17%
d) Sex determining traits
Q.25.
In human zygote male sex is determined by ... ... [ BHU 1995 ]
-
50%
a) Strength of father
-
0%
b) Nutrition of mother
-
50%
c) Composition of required chromosome pair
-
0%
d) None of the above
Q.26.
Addition of individual chromosomes is mutation called .... .. [ JKCMEE 2002 ]
-
20%
a) Polyploidy
-
20%
b) Structural mutation
-
20%
c) Polysomy
-
40%
d) Point mutation
Q.27.
The two eukaryotic organelles responsible for cytoplasmic inheritance are .... ... [ CBSE 2004]
-
25%
a) Lysosomes and mitochondria
-
25%
b) Chloroplasts and lysosomes
-
50%
c) Mitochondria and chloroplasts
-
0%
d) Mitochondria and Golgi complex
Q.28.
Genetic identity of human male is known by ... ... [ CBSE 1997 ]
-
50%
a) Nucleus
-
0%
b) Chloroplasts
-
25%
c) Cytoplasm
-
25%
d) Mitochondria
Q.29.
Which one can induce polyploidy? .... .. [ BHU 1992 ]
-
50%
a) Colchicine
-
25%
b) Acridines
-
0%
c) Ethylene
-
25%
d) Maleic hydrazide
Q.30.
Number of chromosomes in Geometrid Moth is .. ... [ Kerala 2000 ]
-
20%
a) 224
-
20%
b) 250
-
40%
c) 78
-
20%
d) 48
Q.31.
Colour blindness is due to one ... ... [ CPMT 1990 ]
-
25%
a) Recessive allele in females
-
50%
b) Dominant allele in females
-
25%
c) Dominant allele in males
-
0%
d) Recessive allele in males
Q.32.
A segment of chromosomes breaks and rejoins after 180° rotation. It is ... .. [ Kerala 2009 ]
-
25%
a) Duplication
-
25%
b) Reciprocal translocation
-
50%
c) Interstitial translocation
-
0%
d) Inversion
Q.33.
A few normal seedlings of tomato were kept in a dark room. After a few days they were found to have become white-coloured like albinos. Which of the following terms will you use to describe them? …[AIPMT 2014]
-
50%
a) Etiolated
-
0%
b) Defoliated
-
0%
c) Mutated
-
50%
d) Embolised
Q.34.
The movement of a gene from one linkage group to another is called: …[AIPMT 2015] Explanation is provided please click on
-
50%
a) Crossing over
-
0%
b) Inversion
-
25%
c) Duplication
-
25%
d) Translocation
Explanation
Q.35.
Which is the most common mechanism of genetic variation in the population of a sexually-reproducing organism? …[AIPMT 2015]
-
67%
a) Recombination
-
0%
b) Transduction
-
33%
c) Chromosomal aberrations
-
0%
d) Genetic drift
Q.36.
Given below is a pedigree chart of a family with five children. It shows the inheritance of attached ear lobes as opposed to the free ones. The squares represent the male individuals and circles the female individuals, which one of the following conclusions drawn is correct ?
-
25%
a) The parents are homozygous recessive
-
0%
b) The trait is Y-linked
-
75%
c) The parents are homozygous dominant
-
0%
d) The parents are heterozygous
Q.37.
An abnormal human baby with 'XXX' sex chromosomes was born due to: …[AIPMT 2015]
-
25%
a) fusion of two sperms and one ovum
-
50%
b) formation of abnormal sperms in the father
-
25%
c) formation of abnormal ova in the mother
-
0%
d) fusion of two ova and one sperm
Q.38.
Which of the following most appropriately describes haemophilia ? …[AIPMT-2016]
-
0%
a) Recessive gene disorder
-
75%
b) X - linked recessive gene disorder
-
25%
c) Chromosomal disorder
-
0%
d) Dominant gene disorder
Q.39.
In higher vertebrates, the immune system can distinguish self-cells and non-self. If this property is lost due to genetic abnormality and it attacks self cells, then it leads to :- …[AIPMT-2016]
-
25%
a) Allergic response
-
0%
b) Graft rejection
-
75%
c) Auto-immune disease
-
0%
d) Active immunity
Q.40.
Pick out the correct statements : …[AIPMT-2016] (a) Haemophilia is a sex-linked recessive disease (b) Down's syndrome is due to aneuploidy (c) Phenylketonuria is an autosomal recessive gene disorder. (d) Sickle cell anaemia is a X-linked recessive gene disorder
-
0%
a) (a) and (d) are correct
-
50%
b) (b) and (d) are correct
-
50%
c) (a), (c) and (d) are correct
-
0%
d) (a), (b) and (c) are correct
Q.41.
Which of the following statements is not true for cancer cells in relation to mutations ? …[AIPMT-2016]B5
-
67%
a) Mutations in proto-oncogenes accelerate the cell cycle.
-
0%
b) Mutations destroy telomerase inhibitor.
-
33%
c) Mutations inactive the cell control.
-
0%
d) Mutations inhibit production of telomerase.
Q.42.
A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is containing more number of chromosomes as compared to other dividing cells. This would result in :- …[AIPMT-2016]
-
25%
a) Aneuploidy
-
25%
b) Polyploidy
-
50%
c) Somaclonal variation
-
0%
d) Polyteny
Q.43.
Variation in gene frequencies within populations can occur by chance rather than by natural selection. This is referred to as …[NEET 2013]
-
25%
a) Genetic flow
-
50%
b) Genetic drift
-
25%
c) Random mating
-
0%
d) Genetic load
Q.44.
The incorrect statement with regard to Haemophilia is ….[NEET 2013]
-
33%
a) It is a sex-linked disease
-
33%
b) It is a recessive disease
-
33%
c) It is a dominant disease
-
0%
d) A single protein involved in the clotting of blood is affected
Q.45.
A disease caused by an autosomal primary non-disjunction is ….[NEET- 2017]
-
20%
a) Down's syndrome
-
60%
b) Klinefelter's syndrome
-
20%
c) Turner's syndrome
-
0%
d) Sickle cell anemia
Q.46.
A colour blind man marries a woman with normal sight who has no history of colour blindness in her family. What is the probability of their grandson being colour blind ? [ ReAIPMT 2015]
-
40%
a) 0.25
-
20%
b) 0.5
-
0%
c) 1
-
40%
d) Nil
Q.47.
Select the correct statement ..[ NEET 2018]
-
25%
a) Franklin Stahl coined the term "linkage".
-
25%
b) Punnett square was developed by a British scientist.
-
50%
c) Spliceosomes take part in translation.
-
0%
d) Transduction was discovered by S. Altman.
Q.48.
A woman has an X-linked condition on one of her X chromosomes. This chromosome can be inherited by
-
33%
a) Only daughters
-
33%
b) Only sons
-
0%
c) Only grandchildren
-
33%
d) Both sons and daughters
Q.49.
Albinism is due to hereditary deficiency of enzyme .... ... [BHU 2003]
-
25%
a) Amylase
-
25%
b) Carbonic anhydrase
-
50%
c) Acetyl choline esterase
-
0%
d) Tyrosinase
Q.50.
ne centimorgan is equal to recombination frequency of .... ... [ DPMT 2005 ]
-
33%
a) 1
-
33%
b) 0.1
-
33%
c) 10
-
0%
d) 0.01