MCQ Questions
Q.1.
The clearance of what substance provides the best estimate of renal blood flow rate?
  • 0%
    INULIN
  • 0%
    glucose
  • 0%
    OSMOLARITY
  • 0%
    PAH
Q.2.
Changes in mean arterial pressure have the potential to alter glomerular filtration rate by directlyaltering which of the following?
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    glomerular capillary hydrostatic pressure
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    detrusor and the internal urethral sphincter
  • 0%
    glomerular filtration pressure
  • 0%
    Bowman's capsule oncotic pressure
Q.3.
Located entirely within the cortex, reabsorption of water and certain solutes from which region isunder hormonal control?
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    detrusor muscle only.
  • 0%
    basement membrane
  • 0%
    distal tubule
  • 0%
    antidiuretic hormone
Q.4.
Which of the following pressures across the glomerular capillaries approaches zero?
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    Bowman's capsule
  • 0%
    left the filtrate iso-osmotic
  • 0%
    glomerular filtration rate × plasma concentration of solute
  • 0%
    Bowman's capsule oncotic pressure
Q.5.
Which cells of the distal tubule secrete a paracrine in response to changes in the filtrate flow rate? 8
  • 0%
    C) (PGC +ȱΔBC) - (PBC +ȱΔGC)
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    macula densa
  • 0%
    basement membrane
  • 0%
    macula densa cells
Q.6.
What is the brush border?
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    filtration fraction
  • 0%
    apical membrane of renal tubule epithelial cells
  • 0%
    microvilli on the apical membrane of the proximal tubule
  • 0%
    glomerular filtration rate × plasma concentration of solute
Q.7.
The clearance of which of the following substances is normally zero?
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    PAH
  • 0%
    clearance
  • 0%
    glucose
  • 0%
    kidneys
Q.8.
How does the sympathetic nervous system decrease glomerular filtration rate?
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    glomerular filtration rate × plasma concentration of solute
  • 0%
    reabsorption
  • 0%
    stimulates constriction of both the afferent and efferent arterioles
  • 0%
    glomerular capillary osmotic pressure : filtration
Q.9.
In terms of controlling micturition, the somatic nervous system innervates the ________, theparasympathetic nervous system innervates the ________, and the sympathetic nervous systeminnervates the ________.
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    external urethral sphincter : detrusor muscle : internal urethral sphincter
  • 0%
    ureter : urethra
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    secretion into the renal tubules
  • 0%
    flow of tubular fluid : constrict the afferent arteriole
Q.10.
Tubular epithelial cells of the collecting duct and distal tubule contain receptors for what hormonethat stimulates water reabsorption?
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    antidiuretic hormone
  • 0%
    ureter : urethra
  • 0%
    distal tubule
  • 0%
    stretch receptors
Q.11.
Within the kidneys, what membrane has microvilli?
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    FILTER LOAD
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    apical membrane of renal tubule epithelial cells
  • 0%
    microvilli on the apical membrane of the proximal tubule
  • 0%
    glomerular filtration rate × plasma concentration of solute
Q.12.
What are the specialized cells of the juxtaglomerular apparatus in the distal tubule called?
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    macula densa
  • 0%
    Bowman's capsule
  • 0%
    macula densa cells
  • 0%
    clearance
Q.13.
If the amount of solute excreted per minute is greater than the filtered load, then the NET effect onthe solute is
  • 0%
    C) (PGC +ȱΔBC) - (PBC +ȱΔGC)
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    glomerular filtration pressure
  • 0%
    decrease in surface area of capillaries available for filtration
  • 0%
    secretion into the renal tubules
Q.14.
Where does blood leaving the glomerulus go next?
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    FILTER LOAD
  • 0%
    basement membrane
  • 0%
    efferent arteriole
  • 0%
    Bowman's capsule
Q.15.
Which of the following equations is correct for calculating the filtered load?
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    microvilli on the apical membrane of the proximal tubule
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    glomerular filtration rate × plasma concentration of solute
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    detrusor and the internal urethral sphincter
  • 0%
    peritubular and vasa recta, respectively
Q.16.
What is the (urine concentration × urine flow rate)/plasma concentration equal to?
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    clearance
  • 0%
    nephron
  • 0%
    macula densa
  • 0%
    FILTER LOAD
Q.17.
Which of the following conditions would increase glomerular filtration pressure?
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    renal artery, segmental arteries, interlobar arteries, arcuate arteries, interlobular arteries,afferent arteriole, glomerulus, efferent arteriole (R.S.I.A.I.A.G)
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    Which of the following conditions would increase glomerular filtration pressure?
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    macula densa
  • 0%
    The detrusor muscles contract, muscles of the internal urethral sphincter relax, and muscles ofthe external urethral sphincter relax
Q.18.
The diffusion of water across a tubule is driven by differences in ________ across the membrane.
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    glucose
  • 0%
    distal tubule
  • 0%
    stretch receptors
  • 0%
    OSMOLARITY
Q.19.
Substance X is freely filtered at the glomerulus. 3 mmole X is filtered, 2 mmole X is reabsorbed, and2 mmole X is secreted per minute. How much X is excreted per minute?
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    basement membrane
  • 0%
    INULIN
  • 0%
    2 MMOLE
  • 0%
    distal tubule
Q.20.
Which of the four Starling forces for glomerular filtration is incorrectly paired with the direction itfavors (filtration or absorption)?
  • 0%
    reabsorption
  • 0%
    Bowman's capsule oncotic pressure
  • 0%
    glomerular filtration rate × plasma concentration of solute
  • 0%
    glomerular capillary osmotic pressure : filtration
Q.21.
If the glomerular filtration rate is 150 mL/min, renal blood flow is 750 mL/min, and the plasmaconcentration of solute X is 10 ng/mL, then what is the filtration fraction?
  • 0%
    reabsorption
  • 0%
    juxtamedullary nephrons
  • 0%
    PAH
  • 0%
    20%
Q.22.
What is the excretion rate/plasma concentration equal to?
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    macula densa
  • 0%
    renal blood flow
  • 0%
    clearance
  • 0%
    filtration fraction
Q.23.
In tubuloglomerular feedback, an increase in glomerular filtration rate would increase the________, thereby stimulating the release of a paracrine factor from the macula densa that would________.
  • 0%
    peritubular and vasa recta, respectively
  • 0%
    decrease in surface area of capillaries available for filtration
  • 0%
    flow of tubular fluid : constrict the afferent arteriole
  • 0%
    Which of the following conditions would increase glomerular filtration pressure?
Q.24.
If the glomerular filtration rate is 150 mL/min, renal blood flow is 750 mL/min, and the plasmaconcentration of solute X is 10 ng/mL, then what is the filtered load of X?
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    INULIN
  • 0%
    1500 ng/min
  • 0%
    secretion into the renal tubules
  • 0%
    20%
Q.25.
Which layer of the filtration barrier in Bowman's capsule is the primary barrier to the movement ofprotein from the capillary?
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    detrusor muscle only.
  • 0%
    basement membrane
  • 0%
    macula densa
  • 0%
    C) (PGC +ȱΔBC) - (PBC +ȱΔGC)
Q.26.
Most reabsorption occurs in the ________ and is ________.
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    apical membrane of renal tubule epithelial cells
  • 0%
    Bowman's capsule
  • 0%
    secretion into the renal tubules
  • 0%
    proximal tubule : not regulated
Q.27.
What is the sum of Starling's forces within the renal corpuscle called?
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    glomerular filtration pressure
  • 0%
    left the filtrate iso-osmotic
  • 0%
    glomerular filtration rate × plasma concentration of solute
  • 0%
    Bowman's capsule oncotic pressure
Q.28.
Which equation describes the calculation of glomerular filtration pressure (BC = Bowman's capsuleand GC = glomerular capillary)?
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    macula densa cells
  • 0%
    C) (PGC +ȱΔBC) - (PBC +ȱΔGC)
  • 0%
    secretion into the renal tubules
  • 0%
    peritubular and vasa recta, respectively
Q.29.
What are a small percentage of the nephrons in the kidneys that function in the maintenance of theosmotic gradient in the medullary region of the kidney called?
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    juxtamedullary nephrons
  • 0%
    macula densa
  • 0%
    glomerular capillary hydrostatic pressure
  • 0%
    glomerular filtration pressure
Q.30.
Which capillaries branch from efferent arterioles of cortical nephrons and which branch fromefferent arterioles of juxtamedullary nephrons?
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    glomerular capillary hydrostatic pressure
  • 0%
    glomerular filtration pressure
  • 0%
    peritubular and vasa recta, respectively
  • 0%
    glomerular filtration rate × plasma concentration of solute
Q.31.
Which muscle(s) that regulate(s) micturition is/are under involuntary control?
  • 0%
    detrusor and the internal urethral sphincter
  • 0%
    renal artery, segmental arteries, interlobar arteries, arcuate arteries, interlobular arteries,afferent arteriole, glomerulus, efferent arteriole (R.S.I.A.I.A.G)
  • 0%
    glomerular filtration pressure
  • 0%
    Bowman's capsule oncotic pressure
Q.32.
In older children and adults, the cerebral cortex is able to block micturition by inhibiting nerveactivity to the
  • 0%
    distal tubule
  • 0%
    detrusor muscle only.
  • 0%
    basement membrane
  • 0%
    antidiuretic hormone
Q.33.
In diabetes mellitus, why does polyuria occur?
  • 0%
    apical membrane of renal tubule epithelial cells
  • 0%
    The detrusor muscles contract, muscles of the internal urethral sphincter relax, and muscles ofthe external urethral sphincter relax
  • 0%
    Hyperglycemia causes some glucose to remain in the renal tubules which pulls water with itby osmosis
  • 0%
    FILTER LOAD
Q.34.
Contraction of mesangial cells results in a(n) ________, which decreases glomerular filtration
  • 0%
    Which of the following conditions would increase glomerular filtration pressure?
  • 0%
    external urethral sphincter : detrusor muscle : internal urethral sphincter
  • 0%
    decrease in surface area of capillaries available for filtration
  • 0%
    glomerular capillary hydrostatic pressure
Q.35.
What is the GFR × plasma concentration equal to?
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    filtration fraction
  • 0%
    renal blood flow
  • 0%
    nephron
  • 0%
    FILTER LOAD
Q.36.
What is the GFR/renal plasma flow equal to?
  • 0%
    renal blood flow
  • 0%
    filtration fraction
  • 0%
    FILTER LOAD
  • 0%
    Bowman's capsule
Q.37.
Filtration occurs across which capillary bed?
  • 0%
    clearance
  • 0%
    nephron
  • 0%
    FILTER LOAD
  • 0%
    glomerulus