Among the following which one is not the approach to the local alignment?
Smith-Waterman algorithm
K-tuple method
Words method
Needleman-Wunsch algorithm
Q.2.
The legless condition that is observed in several groups of extant reptiles is the result of
their common ancestor having been legless
a shared adaptation to an arboreal (living in trees) lifestyle
several instances of the legless condition arising independently of each other
individual lizards adapting to a fossorial (living in burrows) lifestyle during their lifetimes
Q.3.
The scientific discipline concerned with naming organisms is called -
taxonomy
cladistics
binomial nomenclature
systematics
Q.4.
Which of the following does not describe local alignment algorithm?
Score can be negative
Negative score is set to 0
First row and first column are set to 0 in initialization step
In traceback step, beginning is with the highest score, it ends when 0 is encountered
Q.5.
Which information was most important to the development of genetic engineering techniques?
the observation of nondominant alleles
the discovery of lethal genes
the formulation of Punnett squares
the structure of the DNA molecule
Q.6.
Name a way that genetic engineering in plants is beneficial
Decreased crop yield
Decreased resistance to disease
Increased resistance to disease
Increased pests
Q.7.
When did Smith–Waterman first describe the algorithm for local alignment?
1950
1970
1981
1925
Q.8.
Which of the following does not describe local alignment?
A local alignment aligns a substring of the query sequence to a substring of the target sequence
A local alignment is defined by maximizing the alignment score, so that deleting a column from either end would reduce the score, and adding further columns at either end would also reduce the score
Local alignments have terminal gaps
The substrings to be examined may be all of one or both sequences; if all of both are included then the local alignment is also global
Q.9.
Genetic engineering has produced goats whose milk contains proteins that can be used as medicines. This effect was produced by
mixing genes into the milk
injecting genes into the goats udders
inserting foreign genes into fertilized goat eggs
genetically modifying the nutritional needs of the goats offspring
Q.10.
Chromosomal rearrangements due to insertion sequences have apparently contributed to the evolution of several human pathogens.
TRUE
FALSE
Q.11.
An organism that is produced by asexual reproduction and that is genetically identical to its parent; to make a genetic duplicate
cloning by nuclear transfer
gene therapy
clone
Human Genome Project
Q.12.
Which alignment is useful to detect the highly similar sequences.
Pairwise
Local
Global
MSA
Q.13.
The choice of a suitable multiple sequence alignment method depends on the degree of variation among the sequences.
True
False
Q.14.
In the bootstrap method, the data are resampled by _____ choosing _____ columns from the aligned sequences to produce, in effect, a new sequence alignment of the _____
randomly, horizontal, same length
specifically, vertical, different lengths
randomly, vertical, same length
randomly, vertical, different lengths
Q.15.
Local alignments are more used when _____________
There are totally similar and equal length sequences
Dissimilar sequences are suspected to contain regions of similarity
Similar sequence motif with larger sequence context
Partially similar, different length and conserved region containing sequences
Q.16.
TWhich technology below would probably be the most important to a person who had diabetes and had to take insulin every day?
using recombinant DNA to produce human hormones from bacteria
testing parents for genetic disorders before they have children
engineering fruits and vegetables that resist insects and other pests
C. developing ways to identify criminals through DNA fingerprinting
Q.17.
Vectors
plasmid or virus that contains or carries modified genetic material
They can be used to represent any quantity that has magnitude, has direction
displacement
velocity
Q.18.
BLAST uses a _______ to find matching words, whereas FASTA identifies identical matching words using the _____
substitution matrix, hashing procedure
substitution matrix, blocks
hashing procedure, substitution matrix
ktups, substitution matrix
Q.19.
The gapped portion in the diagonals represents matches in FASTA.
True
False
Q.20.
FASTA is derived from logic of the dot plot.
True
False
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